I recently graduated in medicine from Townsville, Australia, and I still enjoy writing blogs on medicine and pharmacy-related topics. I appreciate writing about my experience on different placements or topics I'm interested in. As English is my second language, writing blogs is a hobby and a fun challenge!
All tagged Formulation
By 1997, in order to increase reliability and reduce variability, Dr D. William Molloy and Timothy I. M. Standish developed the Standardised Mini-Mental State Examination (SMMSE) which provided simple but detailed scoring instructions and reduced any ambiguity from the MMSE.
The 4P factor model formulation is a tool used in psychology and psychiatry where it is deemed necessary and useful. It is quick, easy-to-use and is a structured method to describe, assess and observe your patient’s narrative into a coherent and concise record. In a nutshell: “The formulation asks what is wrong, how it got that way, and what can be done about it”.
The Mental State Examination (MSE) is a tool used in psychology, psychiatry, psychological medicine or anywhere else where it is deemed necessary or useful. It is quick, easy-to-use and is a structured method to describe, assess and observe your patient psychological functioning and mental state.
Appendix of the project with all the tables that did not feature throughout the presenting project. Includes: amount of CBP (grams) used and the surface area utilised (cm2) for each formulation and days, textural profiling for each formulation and dissolution results of all the formulations at day 0, 7, 14, 28 and 60.
The effect of diluting the formulations and the standard formulation containing Dovate® with aqueous cream and homogenizing in a pharmacy setting showed that it was a major factor of slowing down or restricting the release CBP.
A t-test for spreadability was carried out for each formulation and compared to the standard. A dependent t-test, due to being in the same sample, will be used.
The collecting of the results expanded over a 28-day period where 4 dissolutions curves were made. On Day 60 the last dissolution curve was made to expand on the degradation studies.
In analytical chemistry the accurate quantitative measurement of the composition of samples, such as in spectroscopy, would require a calibration using standard samples of known composition. A calibration curve is an analytical method to determine the concentration of an unknown sample solution.
When an active pharmaceutical ingredient (API) is incorporated into a formulation, a rate of release of that API occurs. This is the case with a variety of formulations. Clobetasol and various surfactants that were incorporated into aqueous cream during this experiment followed this concept.
